Antibiotic Substances from Basidiomycetes

Abstract
Two antibiotic substances, named nemotinic acid and nemotin, respectively, were isolated from culture liquids of Poria corticola, P. tenuis. and an unidentified fungus, B841. At. pH 6 or higher and under the influence of temp., nemotin was transformed to nemotin A. The absorption spectrum of nemotinic acid was almost identical to that of nemotin, with peaks at 237, 249, 263, and 277.5 mu; the absorption spectrum of nemotin A had peaks at 231, 242, 272, 289, 307, and 328 mu. Activities of the antibiotic substances were reported for 8 bacteria and 10 fungi. Injns. of nemotinic acid were toxic to white mice.

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