Analysis of Electrostatics and Correlated Motions for Hydride Transfer in Dihydrofolate Reductase
- 16 July 2004
- journal article
- Published by American Chemical Society (ACS) in The Journal of Physical Chemistry B
- Vol. 108 (32) , 12231-12241
- https://doi.org/10.1021/jp048565v
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Functional role for Tyr 31 in the catalytic cycle of chicken dihydrofolate reductaseProteins-Structure Function and Bioinformatics, 2003
- Coupling Interactions of Distal Residues Enhance Dihydrofolate Reductase Catalysis: Mutational Effects on Hydride Transfer RatesBiochemistry, 2002
- Role of water in the catalytic cycle of E. coli dihydrofolate reductaseProtein Science, 2002
- Energetically Most Likely Substrate and Active-Site Protonation Sites and Pathways in the Catalytic Mechanism of Dihydrofolate ReductaseJournal of the American Chemical Society, 2001
- Stretching exercises — flexibility in dihydrofolate reductase catalysisChemistry & Biology, 1998
- Strength of an Interloop Hydrogen Bond Determines the Kinetic Pathway in Catalysis byEscherichia coliDihydrofolate ReductaseBiochemistry, 1998
- Evidence for a Functional Role of the Dynamics of Glycine-121 ofEscherichia coliDihydrofolate Reductase Obtained from Kinetic Analysis of a Site-Directed MutantBiochemistry, 1997
- Molecular Basis for Nonadditive Mutational Effects in Escherichia coli Dihydrofolate ReductaseBiochemistry, 1995
- Nonadditivity of mutational effects at the folate binding site of Escherichia coli dihydrofolate reductaseBiochemistry, 1994
- Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coliBiochemistry, 1987