THE LABORATORY DIAGNOSIS OF EXTRATHYROIDAL HYPERMETABOLISM*

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Abstract
For purposes of differential diagnosis, detns. of the basal metabolic rate, somnolent metabolic rate, uptake and excretion of radio-iodine, and concns. of serum protein-bound iodine and of cholesterol have been made in a series of 49 patients with hypermetabolism. All patients have an elevated basal metabolic rate and many entered the clinic with an initial diagnosis of hyperthyroidism. With the aid of the foregoing tests, all patients were proven to have extrathyroid hypermetabolism. An evaluation of these procedures has been made in order to determine their effectiveness in establishing this diagnosis.

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