The Clinical Toxicity of Terramycin

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Abstract
FOR four months during 1951 and 1952, 5 gm. of Terramycin was given by mouth daily to a group of 70 tuberculous patients at Fitzsimons Army Hospital. Terramycin was used in combination with 2 gm. of streptomycin every third day primarily to study its effect on the rate of emergence of tubercle bacilli resistant to streptomycin. Streptomycin and Terramycin resistance did not occur in any patient receiving the full dosage schedule during or after the treatment period of one hundred and twenty days.1 With the increasing use of Terramycin in the antimicrobial field, it was believed that a brief review . . .