Myeloperoxidase Activity and Bactericidal Function of PMN in Iron Deficiency
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 61 (1) , 10-14
- https://doi.org/10.1159/000207620
Abstract
In children with iron deficiency anemia, bactericidal capacity of polymorphonuclear leukocytes (PMN) and serum opsonic activity were studied. Nitroblue tetrazolium test (NBT), hexose monophosphate (HMP) shunt activation, and myeloperoxidase (MPO) activity of PMN of these cases were also examined. Bactericidal capacity and HMP shunt activation were found to be decreased in iron deficiency anemia (p > 0.001). MPO activity, NBT test, and serum opsonic activity were found to be within normal limits. After 11/2 months of iron therapy there was an improvement in bactericidal capacity and it returned to a normal level after 3 months of therapy.Keywords
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