Fatal hyperpyrexia after withdrawal of levodopa
- 1 February 1984
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 34 (2) , 249
- https://doi.org/10.1212/wnl.34.2.249
Abstract
We studied a patient affected with idiopathic Parkinson's disease and levodopa-induced dyskinesias. Fatal hyperpyrexia followed simultaneous levodopa withdrawal and a decrease in the dosage of diphenhydramine. The clinical features were those of the neuroleptic malignant syndrome. The rapid decrease in dopaminergic activity may have been important in causing the syndrome.Keywords
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