Sequence Differences in the Diagnostic Target Region of the Oocyst Wall Protein Gene of Cryptosporidium Parasites
Open Access
- 1 December 2000
- journal article
- research article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 66 (12) , 5499-5502
- https://doi.org/10.1128/aem.66.12.5499-5502.2000
Abstract
Nucleotide sequences of the Cryptosporidium oocyst wall protein (COWP) gene were obtained from various Cryptosporidium spp. ( C. wrairi , C. felis , C. meleagridis , C. baileyi , C. andersoni , C. muris , and C. serpentis ) and C. parvum genotypes (human, bovine, monkey, marsupial, ferret, mouse, pig, and dog). Significant diversity was observed among species and genotypes in the primer and target regions of a popular diagnostic PCR. These results provide useful information for COWP-based molecular differentiation of Cryptosporidium spp. and genotypes.Keywords
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