Indirect Causes of Congenital Malformations. An Analysis of 212 Cases

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Abstract
The incidence of congenital malformations in the material of the IInd Clinic of Obstetrics and Gynecology of the Warsaw Medical Academy from 1959 to 1964 amounted to 1.9%. The most frequent probable etiological factors are maternal infections and carbohydrate metabolism disorders during pregnancy. A correlation between maternal carbohydrate metabolism disturbances and malformations of the CNS has been noted as well as a probable correlation between maternal iron deficiency and subsequent circulatory and skeletal malformations. The latter merits further investigation. It seems necessary to carry out a many-sided examination with a wide range of laboratory tests in cases of pathological pregnancy, and to take a genetic history of the families of children with congenital malformation.

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