A Phosphatidylinositol 3-Kinase/p70 Ribosomal S6 Protein Kinase Pathway Is Required for the Regulation by Insulin of the p85α Regulatory Subunit of Phosphatidylinositol 3-Kinase Gene Expression in Human Muscle Cells
Open Access
- 1 November 1999
- journal article
- Published by Elsevier
- Vol. 274 (48) , 34005-34010
- https://doi.org/10.1074/jbc.274.48.34005
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Insulin Stimulation of the Fatty Acid Synthase Promoter Is Mediated by the Phosphatidylinositol 3-Kinase PathwayJournal of Biological Chemistry, 1998
- Overexpression of a Constitutively Active Form of Phosphatidylinositol 3-Kinase Is Sufficient to Promote Glut 4 Translocation in AdipocytesJournal of Biological Chemistry, 1996
- Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms.Journal of Clinical Investigation, 1996
- Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle.Journal of Clinical Investigation, 1996
- Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects.Journal of Clinical Investigation, 1995
- The Insulin-dependent Biosynthesis of GLUT1 and GLUT3 Glucose Transporters in L6 Muscle Cells Is Mediated by Distinct PathwaysJournal of Biological Chemistry, 1995
- Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.Journal of Clinical Investigation, 1995
- Normal Activation of P70 S6 Kinase by Insulin in Cells Overexpressing Dominant Negative 85-kDa Subunit of Phosphoinositide 3-KinaseBiochemical and Biophysical Research Communications, 1995
- Does Mitogen-Activated-Protein Kinase have a Role in Insulin Action?. The Cases for and AgainstEuropean Journal of Biochemistry, 1995
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976