Regulatory role of the ATPase inhibitor protein on proton conduction by mitochondrial H+‐ATPase complex
Open Access
- 9 March 1987
- journal article
- Published by Wiley in FEBS Letters
- Vol. 213 (1) , 67-72
- https://doi.org/10.1016/0014-5793(87)81466-7
Abstract
This study shows that the natural inhibitor protein of mitochondrial H+‐ATPase complex (IF1) inhibits, in addition to the catalytic activity, the proton conductivity of the complex. The inhibition of ATPase activity by IF1 is less effective in the purified F1 than in submitochondrial particles where F1 is bound to F0. No inhibition of H+ conductivity by F0 is observed in F1‐depleted particlesKeywords
This publication has 37 references indexed in Scilit:
- Effect of diamide on proton translocation by the mitochondrial H+-ATPaseBiochemical and Biophysical Research Communications, 1985
- Interaction between the mitochondrial ATP synthetase and ATPase inhibitor proteinFEBS Letters, 1985
- Primary structure of a regulating factor, 15 kDa protein, of ATP synthase in yeast mitochondriaFEBS Letters, 1984
- Interaction of F1-ATPase, from ox heart mitochondria with its naturally occurring inhibitor protein. Studies using radio-iodinated inhibitor proteinBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1983
- Effect of Thiol Reagents on the Proton Conductivity of the H+-ATPase of MitochondriaEuropean Journal of Biochemistry, 1982
- Functional and immunological characterization of ATPase inhibitor proteins from heart, liver and yeast mitochondriaFEBS Letters, 1982
- Radiolabeling of natural adenosine triphosphatase inhibitor with phenyl[14C]isothiocyanate and study of its interaction with mitochondrial adenosine triphosphatase. Localization of inhibitor binding sites and stoichiometry of bindingBiochemistry, 1980
- Preparation and characterization of homogeneous coupling factor 6 from bovine heart mitochondriaBiochemical and Biophysical Research Communications, 1976
- Studies of the Energy‐Transfer System of Submitochondrial ParticlesEuropean Journal of Biochemistry, 1968