Metastasizing tumors from serum-supplemented and serum-free cell lines from a C57BL mouse lung tumor.

  • 1 March 1976
    • journal article
    • Vol. 36  (3) , 1049-55
Abstract
A tissue culture cell line was established from an alveologenic lung carcinoma from a C57BL/lcrf-at mouse. The cells can be maintained in a completely defined serum-free medium. Tumors derived from the tissue culture cells grown in serum-free or serum-supplemented medium give rise to lung metastases. The ultrastructure of the tissue culture cells in both media is similar to that of spontaneous or induced alveologenic mouse lung tumors.

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