The Formation of Photoreactivable Damage by Direct Excitation of DNA in X-irradiatedE. ColiCells
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 47 (1) , 49-56
- https://doi.org/10.1080/09553008514550071
Abstract
The role of the direct excitation process in the formation of photoreactivable damage (pyrimidine dimers) in E. coli WP2 hcr−exr− cells has been studied. The pyrimidine dimers were detected by photoreactivation following anoxic irradiation by X-rays (220 kVp). The dose modifying factor (DMF) is 1·28 ± 0·09. A biophysical model is used for a theoretical examination of the importance of the direct excitation process in the formation of photoreactivable damage and the experimental data are consistent with this model.Keywords
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