Partial trisomy 3q due to a de novo translocation t(X;3) (p21;q12)

Abstract
A patient with several congenital malformations, principally in the face, cardiovascular system and genitalia, had the karyotype (46,X,der(X),t,X;3)(Xqter .fwdarw. p21::3q12 .fwdarw. 3qter). A comparison of the clinical and cytogenetical findings with similar cases in the literature led to the conclusion that a partial trisomy 3q is the most likely cause for the symptoms in this patient.