Polyostotic Fibrous Dysplasia: Review of the Literature with Two Additional Cases

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Abstract
History Ever since the publication of von Recklinghausen's (91) monograph in 1882, the literature on fibrocystic disease of bone has become increasingly abundant and confusing. In retrospect, it is obvious that von Recklinghausen described not one disease but a number of heterogeneous, unrelated pathologic conditions which had, as a common denominator, the production of fibrocystic-like bone changes. For many years, his name has been associated with hyperparathyroidism and neurofibromatosis. As a matter of fact, it is not unlikely that some of his original cases may have been examples of polyostotic fibrous dysplasia. The latter disease entity was first popularized in this country by Albright and his co-workers in 1937 (3) and by Lichtenstein in 1938 (50). It had been known on the continent for some time prior to its recognition here. In 1922, Wieland (98) in Germany wrote an article entitled Osteitis Fibrosa Cystica Congenita, which may well have been a discussion of polyostotic fibrous dysplasia. The sa...

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