A METHOD FOR THE CONCENTRATION OF POLIOMYELITIS VIRUS IN NASOPHARYNGEAL WASHINGS

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Abstract
In an effort to improve the technique of isolating the virus of poliomyelitis from the nasopharynx in clinical cases of this disease, expts. were performed in which virus has been added and recovered from normal nasopharyngeal washings. Part of each of a series of virus dilutions in these normal nasopharyngeal washings was concentrated through the agency of freezing and evaporating in the presence of normal monkey serum. 7 comparative in-fectivity tests on monkeys from the unconcentrated and concentrated material are descr., of which 4 are considered satisfactory. They indicate that the conc. method here employed enhances the infectivity of the virus containing material.