Pressure jump method with detection of optical rotation and circular dichroism
- 1 June 1978
- journal article
- Published by AIP Publishing in Review of Scientific Instruments
- Vol. 49 (6) , 797-801
- https://doi.org/10.1063/1.1135618
Abstract
A pressure jump technique for fast kinetics using optical rotation and circular dichroism detection is presented and a suitable cell design for both detection methods is discussed. The detectability of changes in optical rotation far away from the Cotton region is considered, and measurements made on a pressure-dependent folding reaction of the protein serum albumin are given as an application.Keywords
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