Demonstration of L.E. Cells at Local Inflammatory Sites in Patients with Systemic Lupus Erythematosus
- 24 November 1960
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 263 (21) , 1052-1055
- https://doi.org/10.1056/nejm196011242632104
Abstract
THE development of lupus cells in patients with systemic lupus erythematosus has been difficult to study, and only limited information is available. The extent to which the L.E.-cell phenomenon occurs in vivo and its importance in the pathophysiology of the disease remain matters of speculation.Rebuck and Berman1 studied the cellular changes leading to the production of L.E. cells on the abraded skin of 2 normal volunteers after the addition of lupus plasma with the serial cover-slip technic. The cells have been found in stagnated blood taken from the fingers of patients with systemic lupus erythematosus.2 This technic, however, did . . .Keywords
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