Effect of testosterone on serotonin and noradrenaline concentrations and taste bud cell number of rat circumvallate papilla

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Abstract
Intramuscular administration of testosterone (T) to male or female rats produced a significant increase in the rate of development of the intermediate type of taste bud cells. T treatment produced a similar effect in rats previously submitted to the in-block or selective removal of the main salivary glands. 5-Hydroxytryptamine (5-HT) and noradrenaline (NA) concentrations in the vallate papilla of normal rats were sensitive to T. The concentration of 5-HT decreased significantly and the concentration of NA increased slightly, both with respect to the controls.

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