In vivo Remineralization of Artificial Enamel Lesions by a Fluoride Dentifrice or Mouthrinse

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Abstract
Acid-softened bovine enamel slabs were mounted in acrylic mandibular removable appliances and worn by 8 male subjects. Control slabs were worn for 4 days without exposure to topical fluoride agents. The test slabs were brushed 4 times a day for 3 days with a 0.24% NaF dentifrice or rinsed 4 times a day for 3 days with a 0.02% APF mouthrinse and worn a 4th day without exposure to the fluoride agent. Microhardness values for both groups of test slabs were significantly higher than controls following intraoral exposure and after in vitro exposure to acid. The uptake of fluoride by both mouthrinse- and dentifrice-treated slabs was significantly higher than the controls.