Development of Co- and Post-Translational Synthetic Strategies to C-Neoglycopeptides
- 24 September 2002
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (21) , 3591-3594
- https://doi.org/10.1021/ol0264861
Abstract
The synthesis of stable, C-linked analogues of glycopeptides is being investigated with two complementary synthetic strategies, co-translational and post-translational glycopeptide synthesis. The key feature of the present approach lies in an effective olefin cross-metathesis reaction that allows formation of both glycoamino acids and glycopeptides.Keywords
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