Biosynthesis of vitamin B12: order of the later C-methylation steps
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 9,p. 585-588
- https://doi.org/10.1039/c39850000585
Abstract
Pulse labelling experiments with [methyl-13C]S-adenosylmethionine (SAM) had previously shown that during the biosynthesis of vitamin B12, the fourth C-methylation site is C-17; new inverted pulse studies show that the remaining four SAM-derived methyl group are introduced in the order 12, 1, 15, 5.Keywords
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