Development of Electrical Activity in Cerebral Hemispheres of the Chick Embryo.

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Abstract
"Spontaneous" electrical activity and that produced by strychnine appear simultaneously on the 13th day of incubation of the Rhode Island Red chick embryo. On the 14th and 15th days the low voltage "early" rhythm gradually increases in frequency and voltage. On the 16th day the high voltage "late" rhythm appears, becoming more constant on the subsequent days. With development of the embryo the strychnine spikes become of shorter duration and higher voltage, pointing to a better synchronization of the neurones. From the 14th day epileptic discharges produced by anoxia, strychnine, Metrazol or drying are observed. Electrical activity of the brain appears in the chick embryo at a critical time in the morphological,biochemical and physiological development.