Detection of Soluble Antigen of Epstein-Barr Virus by the Enzyme-Linked Immunosorbent Assay
- 1 October 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 136 (Supplement) , S324-S328
- https://doi.org/10.1093/infdis/136.Supplement_2.S324
Abstract
The enzyme-linked immunosorbent assay (ELISA) was compared with the micro-complement-fixation test for sensitivity and reliability in detection of antibody to soluble antigen of Epstein-Barr virus. ELISA was found to be more sensitive (up to 160 times more antibody) in detecting levels of antibody than the complement- fixation assay. The ELISA test was shown also to be comparably reliable to the complement-fixation assay in detecting immunity to this antigen; only one false-positive response was found in tests of 21 sera. Because this assay is completely quantifiable, it provides an easy, rapid, and highly sensitive technique for the detection of antibody to antigen of Epstein-Barr virus.Keywords
This publication has 0 references indexed in Scilit: