THE PLASMA LIPOIDS IN ARTERIOSCLEROSIS OBLITERANS

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Abstract
Plasma lipids were studied in a series of 73 cases of arteriosclerosis obliterans without diabetes mellitus and compared with a control series of 200 individuals of various ages who were considered normal. The ranges of the various lipid fractions and total lipids were essentially the same in the 2 groups. However, the mean values for all fractions and for total lipids were definitely and significantly higher in the patients with arteriosclerosis than in the control group. Since the plasma lipids were shown to be essentially normal in thrombo-angiitis obliterans, it was believed that high values for plasma cholesterol and total lipids may be of diagnostic significance in cases where the differentiation between thrombo-angiitis obliterans and arteriosclerosis obliterans is difficult. By the use of diets containing only small amts. of animal fat it was possible to lower the levels of the plasma lipids definitely in 4 out of 8 cases of arteriosclerosis obliterans where these levels were comparatively high. 3 cases were observed where there was the combination of arteriosclerosis obliterans, xanthoma tuberosum of the skin and marked lipemia.