Effects of 2-propyl 2-pentenoic acid on the acquisition of conditioned behavior with negative reinforcement in mice

Abstract
2-Propyl 2-pentenoic acid (PPΔ), at a dose of 6 mg/kg (0.04 mM/kg), has a facilitating action on the acquisition of conditioned avoidance reactions. This effect of PPΔ is correlated with increase of the level of brain gamma-aminobutyric acid, following administration of PPΔ.