Drug Interactions in the Elderly

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Abstract
The incidence of adverse reaction to drugs and of drug interaction increases with age. The types of interaction which may occur are described. The mechanisms underlining pharmacokinetic and pharmacodynamic interactions are described and examples of common drug interactions which may occur in the elderly are given. It is emphasised that the elderly may need to take several drugs for the maintenance of good health and the potential danger of the part played by interaction must be recognised.

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