Proximal Motor Neuropathy in the BB-Wistar Rat
- 1 September 1982
- journal article
- Published by American Diabetes Association in Diabetes
- Vol. 31 (9) , 784-788
- https://doi.org/10.2337/diab.31.9.784
Abstract
Proximal motor neuropathy is a well-recognized neuropathic complication in human diabetes mellitus, due to microvasculopathic changes. Spontaneously diabetic BB-Wistar rats maintained at a moderate severity of diabetes developed structural proximal motor neuropathy after long-standing diabetes. This was caused by multiple infarcts in the spinal ventral roots. Endoneurial Vessels showed occlusions by platelet aggregates and unstriated fibrin, indicative of a hypercoagulability.Keywords
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