Effect of prednisolone on motor end‐plate fine structure: A morphometric study in hamsters

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Abstract
The fine structure of quadriceps motor end‐plates in hamsters was analyzed quantitatively one, two, four, seven, and thirty‐two weeks following intraperitoneal injections of prednisolone. Except for transient increases in postsynaptic length and membrane profile concentration after prednisolone administration at dosages of 4 mg per kilogram of body weight for one week and 2 mg per kilogram for four weeks, mean values for various measurable profiles in the presynaptic and postsynaptic regions showed no significant differences between control and treated animals.