Synthesis and Metabolism of 5beta-Cholestane-3alpha, 7alpha, 12alpha-triol-26-al. Bile Acids and Steroids 161.

Abstract
The partial synthesis of 3[alpha], 7[alpha], 12 [alpha]-trihydroxy-5[beta]-cholest-24-en-26-oic acid and 5[beta]-cholestane-3[alpha], 7 [alpha], 12 [alpha]-triol-26-al is described. Tritium-labeled 5[beta]-cholestane-3[alpha], 7[alpha], 12 [alpha]-triol-26-al was readily converted into 3[alpha], 7[alpha], 12 [alpha]-trihydroxy-5[beta] -cholestan-26-oic acid by the mito-chondrial, the microsomal, and the soluble fractions of rat liver homogenates.