Biochemical markers as prognostic indices in breast cancer
- 1 February 1990
- journal article
- review article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 36 (2) , 188-191
- https://doi.org/10.1093/clinchem/36.2.188
Abstract
Traditional prognostic markers in breast cancer include histological variables such as tumor size, grade, and axillary node status. In recent years some new potential prognostic markers of a biochemical nature have been described: estradiol receptors, progesterone receptors, epidermal growth factor receptors, erbB-2 proto-oncogene, and certain proteolytic enzymes. None of these new markers excels axillary node status as a prognostic marker. Biochemical markers can, however, be evaluated with use of minimal surgery and may help distinguish the minority of aggressive axillary-node-negative breast cancers.Keywords
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