DIURNAL PATTERN OF PLASMA 17-HYDROXYCORTICOSTEROIDS IN PRETECTAL AND TEMPORAL LOBE DISEASE
- 1 June 1961
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 21 (6) , 695-698
- https://doi.org/10.1210/jcem-21-6-695
Abstract
Diurnal patterns of plasma 17-hydroxycorticosteroids were determined in 2 patients with localized pretectal area disease and in 2 with localized temporal lobe disease. All 4 patients exhibited abnormal patterns in contrast to 3 patients with disease localized elsewhere in the central nervous system, all of whom showed normal diurnal patterns. This provides further evidence that the temporal and pretectal areas of the brain are important in the regulation of pituitary release of corticotropin, and of the diurnal pattern of plasma 17-hydroxycorticosteroids, which is a reflection of such release.Keywords
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