Circulating Recombinant Form CRF02_AG in South America
- 1 April 2003
- journal article
- research article
- Published by Mary Ann Liebert Inc in AIDS Research and Human Retroviruses
- Vol. 19 (4) , 329-332
- https://doi.org/10.1089/088922203764969537
Abstract
With the objective of monitoring the distribution of HIV-1 subtypes and circulating recombinant forms (CRFs) in South America, population-based surveillance studies were performed in seven countries. Peripheral blood mononuclear cell, filter paper, fresh blood, and cocultivation samples were collected from HIV-positive patients from Colombia, Ecuador, Peru, Bolivia, Chile, Argentina, and Uruguay, during a 7-year period (1995–2001). DNA was prepared and HIV envelope subtypes were determined by heteroduplex mobility assay and DNA sequencing from 1289 HIV-positive samples. While subtypes B and F were the most commonly observed subtypes, two CRF02_AG strains were detected, in Ecuador. This is the first report of the existence of this CRF in South America.Keywords
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