The Influence of Gender on the Susceptibility to Multiple Sclerosis in Sibships
- 1 June 1991
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 48 (6) , 586-588
- https://doi.org/10.1001/archneur.1991.00530180038014
Abstract
• A population-based study of pairs of relatives (siblings, second- and third-degree) concordant for multiple sclerosis did not show an excess of like-sexed pairs. In addition, data on human lymphocyte antigen typing for sibling pairs concordant for multiple sclerosis did not find an increase in haplotype sharing for like-sexed pairs. These data do not support the notion that sex-related factors influence multiple-sclerosis susceptibility in families.Keywords
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