HORMONAL CONTROL OF THE SECRETION OF THE ENDOMETRIAL GLANDS IN THE MOUSE

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Abstract
Department of Physiology, Royal Veterinary College, Royal College Street, London, NW1 OTU, and *Imperial Cancer Research Fund, Lincolns Inn Fields, London, WC2A 3PX (Received 8 June 1976) Although the endometrial glands form a prominent part of the uterus of rodents, surprisingly little is known of the factors controlling their secretion, or indeed of the function of the secretion. During pregnancy the glands proliferate on the third day after mating in response to the high levels of oestrogen secreted during pro-oestrus (Finn & Martin, 1967, 1973). Secretion, however, does not become apparent in the lumina of the glands until day 6 of pregnancy. The extent of secretion is difficult to quantitate because it is not possible to collect it. However histological sections, especially after staining with the periodic acid-Schiff's (PAS) technique, reveal clearly the presence of a mucopolysaccharide substance in the lumina of the glands so that an approximate subjective assessment

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