Linkage in Control of Allotypic Specificities on Two Different γG-Immunoglobulins
- 30 April 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 148 (3670) , 640-642
- https://doi.org/10.1126/science.148.3670.640
Abstract
Allotypic specificities were identified on two different myeloma proteins and the corresponding normal γG-immunoglobulins of BALB/c mice. When the sera of F2 progeny from a cross between BALB/c mice having the a1 allotype and AL mice having the a4 allotype were tested for these specificities, it was found that the two allotypic specificities of the BALB/c mice were either both present (87 mice) or both absent (36 mice), an indication of linkage in their genetic control.Keywords
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