On the mineralocorticoid and hypertensogenic properties of 16β-Hydroxy-Dehydroepiandrosterone
- 1 August 1976
- journal article
- specialia
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 32 (8) , 1067-1069
- https://doi.org/10.1007/bf01933976
Abstract
Summary Dosages of either 1 or 2 mg daily of 16β-hydroxy-dehydroepiandrosterone, given to mononephretomized, salt-loaded female rats, had no detectable effect upon saline consumption, blood pressure, kallikrein excretion or heart and kidney weight. Its alleged mineralocorticoid properties, as judged by these criteria, were not demonstrable.Keywords
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