COMPARATIVE HAEMODYNAMICS DURING OPERATION, UNREPLACED BLOOD LOSS, AND ANAESTHESIA WITH ETHER OR HALOTHANE IN NITROUS OXIDE AND OXYGEN *

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Abstract
Haemodynamics during operations on ten patients under ether anaesthesia are compared with those during similar operations on ten patients under halothane anaesthesia. Initial cardiac output was greater in the ether group than in ther halothane group and tended to rise. In the halothane group cardiac output fell slightly with time and unreplaced blood loss, and it was associated with lower arterial pressure, stroke index, and heart rate, and with higher central venous pressure. It is concluded that myocardial contractility or distensibility or both are less with halothane than with ether under these conditions. In addition, it appears that systemic blood flow is maintained better with ether in the presence of prolonged operation and unreplaced blood loss than with halothane.

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