Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4‐acetylsulphamethoxazole in the turtle Pseudemys scripta elegans
Open Access
- 1 October 1987
- journal article
- research article
- Published by Taylor & Francis in Veterinary Quarterly
- Vol. 9 (4) , 381-384
- https://doi.org/10.1080/01652176.1987.9694130
Abstract
The turtle Pseudemys scripta elegans is able to hydroxylate and acetylate Sulphamethoxazole in a way that is comparable to man, i.e the rate and yield of hydroxylation equals that of the acetylation. The hydroxy metabolites 5‐hydroxy‐ and N4‐acetyl‐5‐hydroxysulphamethoxazole are not glucuronidated. N4‐acetysulphamethoxazole is neither deacetylated nor hydroxylated.This publication has 10 references indexed in Scilit:
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