Effects of Endotoxin on Hepatic Glycogen Metabolism in Vitro

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Abstract
An in vitro model employing homogenates of mouse liver was developed to study the effects of endotoxin from Sal-monella typhimurium on glycogen metabolism. Studies with this model showed that endotoxin can act directly and that the accelerated loss of glycogen was not related to an increased release of epinephrine. These results indicated that endotoxin acts on the glycogenolytic enzymes.

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