The Nature of Wound Healing

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Abstract
Administration of deca durabolin accelerates development of tensile strength in wounds without affecting collagen or cell content of the wound granulation tissue. This development is accompanied by increased formation of mucopolysaccharide when measured by uptake of S35 labelled sulfate. Clinical experience indicates that mucopolysaccharide and not collagen is the important agent in the healing of wounds. Young tissues have a higher mucopolysaccharide to collagen ratio and heal more rapidly. Collagen deposition may be a nonspecific process and not a fundamental part of healing.