Tumor Cell-Induced Mouse Ascites Fluid as a Source of Viral Antibodies

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Abstract
Mice immunized by multiple injections of either influenza A or Newcastle disease virus produced antibody levels in the Sarcoma 180 cell-induced ascites comparable to the levels found in the blood plasma as measured by the hemagglutination-inhibition test. The infectivity and interfering capacity of influenza viruses could also be neutralized by the specific immune ascites. It was possible to collect at least 10 times more ascites than heart blood.