Placental Alkaline Phosphatase Compared with Human Placental Lactogen and Oestriol in High-Risk Pregnancies
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Gynecologic and Obstetric Investigation
- Vol. 18 (4) , 206-211
- https://doi.org/10.1159/000299082
Abstract
Serum levels of placental alkaline phosphatase (PLAP), human placental lactogen (HPL) and oestriol (E3) were investigated in 33 women with high-risk pregnancies. In pregnancies complicated by intrauterine growth retardation (IUGR) low PLAP values were constantly recorded. HPL values showed a similar pattern while E3 levels were between normal mean and the lower limit of –2 SD. A clear differentiation between IUGR and pre-eclampsia was achieved by the simultaneous determination of PLAP and HPL. It is suggested that PLAP determinations may be more informative than E3 to detect placental insufficiency.Keywords
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