Das kongenitale adrenogenitale Syndrom (AGS) im geschlechtsreifen Alter. Bericht über 22 Fälle*

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Abstract
22 adolescent and adult female patients - 15 to 37 years old - with the Congenital Adrenogenital Syndrome (AGS) were examined. In only 7 cases the disease was diagnosed immediately after birth. Among 16 patients, which had already undergone a reconstructive operation of the external genitalia, only 5 were satisfied with its cosmetic and functional results. 11 women could not do a sexual intercourse due to the malformed external genitalia. Menarche occurred spontaneously in only 10 cases under cortisone-therapy. At the time of investigation only 4 patients had regular menstrual-cycles. Adolescents suffering from AGS should be referred to a pediatric-gynecologist not later than puberty to assure an individual guidance relating to menstruation, surgical intervention, sexual-life and fertility.

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