Biofilm Formation by Hyperpiliated Mutants of Pseudomonas aeruginosa
Open Access
- 1 April 2003
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 185 (7) , 2374-2378
- https://doi.org/10.1128/jb.185.7.2374-2378.2003
Abstract
Under static growth conditions, hyperpiliated, nontwitching pilT and pilU mutants of Pseudomonas aeruginosa formed dense biofilms, showing that adhesion, not twitching motility, is necessary for biofilm initiation. Under flow conditions, the pilT mutant formed mushroom-like structures larger than those of the wild type but the pilU mutant was defective in biofilm formation. Therefore, twitching motility affects the development of biofilm structure, possibly through modulation of detachment.Keywords
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