The Kinetic Factors That Determine the Affinity and Selectivity for Slow Binding Inhibition of Human Prostaglandin H Synthase 1 and 2 by Indomethacin and Flurbiprofen

This publication has 17 references indexed in Scilit:

• Etodolac selectively inhibits human prostaglandin G/H synthase 2 (PGHS-2) versus human PGHS-1
  European Journal of Pharmacology, 1995
• Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase.
  Proceedings of the National Academy of Sciences, 1994
• Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system
  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1994
• Solvent Isotope Effects on the Onset of Inhibition of Porcine Pepsin by Pepstatin
  Biochemistry, 1994
• Studies on the Kinetic and Chemical Mechanism of Inhibition of Stromelysin by an N-(Carboxyalkyl)dipeptide
  Biochemistry, 1994
• The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
  Nature, 1994
• Mitogen‐inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs
  Drug Development Research, 1992
• Possible role for water dissociation in the slow binding of phosphorus-containing transition-state-analog inhibitors of thermolysin
  Biochemistry, 1987
• Time-dependent inhibition of platelet cyclo-oxygenase by indomethacin is slowly reversible
  Prostaglandins, 1986
• The slow-binding and slow, tight-binding inhibition of enzyme-catalysed reactions
  Trends in Biochemical Sciences, 1982