RECOVERY OF HERPES SIMIAE (B-VIRUS) FROM BOTH PRIMARY AND LATENT INFECTIONS IN RHESUS-MONKEYS

  • 1 January 1975
    • journal article
    • research article
    • Vol. 56  (6) , 485-488
Abstract
The suspected ability of herpes simiae (B virus) to persist in a latent form was confirmed in rheusus monkeys. The virus was recovered from primary oral lesions of 2 young monkeys and again , 6 mo. after disappearance of symptoms, from cultures of Gasserian ganglia taken fro the same individuals. B virus was identified by its effects in vivo and in vitro and in cross neutralization tests with antisera to reference B virus and herpes simplex virus. Tests showed that the same virus was present in oral lesions and in ganglia. The 1-way immunological relationship between herpes simplex virus and B virus was clearly shown in results of cross neutralization tests.