A note on the structure of spindle fibres

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Abstract
Single mitotic cells from cultures of newt heart tissue or from human fibroblast cultures were burst on a dilute calcium chloride solution and negatively stained on electron-microscope grids. The electron-microscopic appearance of spindle fibres negatively stained with uranyl acetate and with ammonium molybdate is described. As in the case of fibres from sperm tails, the spindle fibres were found to be tubular and the wall was seen to be composed of longitudinal fibrils about 35 Å in diameter.