Structures of Fifteen Oligosaccharides Isolated from New‐Born Meconium
- 1 July 1981
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 117 (2) , 291-300
- https://doi.org/10.1111/j.1432-1033.1981.tb06336.x
Abstract
Newborn meconium contains at least 100 oligosaccharides. The isolation and characterization of the major constituents are described. The structure elucidation of 15 neutral and acidic oligosaccharides was carried out by methylation analysis, mass spectrometry and 360-MHz 1H-NMR spectroscopy. The oligosaccharides accumulating in human meconium are probably products of the catabolism of the O- and N-linked carbohydrate chains of glycoproteins. Endo-N-acetyl-.alpha.-D-galactosaminidase, endo-.beta.-D-galactosidase and endo-N-acetyl-.beta.-D-glucosaminidase are apparently involved in the production of these compounds.This publication has 18 references indexed in Scilit:
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