Tissue Reaction to Implantation of Collagen Film

Publisher Website
Google Scholar
Abstract
A new modified collagen film was investigated to evaluate the tissue reaction and absorption time after implantation in rabbit muscle, and in a human model where collagen was implanted in the prostatic cavity during operation. Clinical follow-up by cytoscopy and biopsy was made 1 wk postoperatively. The animal results showed that for 6 wk after implantation there was a cellular reaction associated with phagocytosis of the collagen film. Then a scar was formed similar to that in the controls. The human results showed a similar tissue reaction and no adverse effects from the collagen film.