Neutrophil C5a receptor and the outcome in a rat model of sepsis
Open Access
- 15 August 2003
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 17 (13) , 1-17
- https://doi.org/10.1096/fj.03-0009fje
Abstract
Complement fragment 5a (C5a)–C5a receptor (C5aR) signaling plays an essential role in neutrophil innate immunity. Blockade of either the ligand or the receptor improves survival rates in experimental...Keywords
Funding Information
- National Institutes of Health (GM-61656, HL-31963)
- American Lung Association (RG-057-N)
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